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If Lexapro side effects occur. Lexapro works by increasing the amount of serotonin, a natural substance in the brain that may become unbalanced and cause depression or anxiety. With a monoamine oxidase inhibitor. Do have problems note that they are much less severe than they were on older anti-depressants. This medication may cause dizziness or drowsiness. Evidence suggests an imbalance of serotonin, a natural substance in the brain that may become unbalanced and cause depression or anxiety. Lexapro does cause problems when you are operating a vehicle or driving heavy machinery. Lexapro is used to treat depression and generalized anxiety disorder. Lexapro anti depressant has helped millions and is continuing to help millions.